Topics & People

The official dietary guidance chart which Makary's FDA has 'flipped upside down' to prioritize protein over a historical focus on carbohydrates, citing decades of flawed science and industry influence.

The strategic rivalry between the United States and China for dominance in biopharma innovation, life sciences, and biomedical research.

The multi-stage process, including clinical trials, for getting new drugs to market. The FDA is reforming this process to reduce the typical 10-12 year timeline.

A series of 42 major changes implemented by Marty Makary at the FDA to challenge the status quo, increase efficiency, and accelerate the approval of drugs and therapies.

Considered the biggest and most important biotech conference globally, held in San Francisco.

The current FDA Commissioner in the Trump administration, a surgeon from Johns Hopkins, and author, leading significant reforms at the agency.

A telecommunications company whose famous 'You Will' commercial predicted remote work from the beach, and for whom McKinsey produced an infamous report in the 80s predicting mobile phones would not take off.

Apple's revolutionary music player, mentioned as the successor to the Sony Discman, which solved the problems of both durability and digital fidelity in portable music.

A historical mobile device with a physical keyboard, brought out from the 'time capsule' to represent a once-dominant technology that was eventually disrupted.

Aggressive Chinese EV manufacturer seen as a major competitor capable of disrupting the US auto market if tariffs were lifted.

Fraudulent startup that raised $900M at a $9B valuation.

The choice facing large, existing enterprises: transform using new technologies like AI or risk becoming obsolete. This is distinct from traditional private equity, which optimizes rather than transforms.