Topics & People

Rapamycin
ScientificConcept

An immunosuppressant drug used in longevity protocols to slow aging.

Psilocybin
ScientificConcept

A psychedelic compound shown to dampen the default mode network and drive neuroplasticity.

DMT
ScientificConcept

A powerful psychedelic molecule, which 5-MeO-DMT is derived from or compared against.

5-MeO-DMT
Technology

A highly potent psychedelic compound used by Bryan Johnson as an experimental longevity therapy.

Eight Sleep
Organization

A sleep technology company that sponsors the podcast.

The bottleneck in AI computing related to memory and storage supply.

Forge
Technology

A platform providing infrastructure and access to secondary market trading for private companies.

Mac Mini
Technology

Apple desktop computer proposed as a local home AI server.

An AI agent product that competes with OpenClaw, part of a larger trend of companies trying to create proprietary agentic systems.

Comet Browser
Technology

Agentic browsing tool developed by Perplexity.

Co-CEO and co-founder of IREN.

CEO of Mistral AI.