Topics & People
The set of actions undertaken by a central bank to manipulate the money supply and credit conditions to stimulate or restrain economic activity. The Fed's monetary policy is a central point of contention.
An educational program for startup founders created by Jason Calacanis, which is expanding globally to locations like Riad.
A research group that partnered with OpenAI to experimentally validate the proteins predicted by the GPT-4B micro model, confirming their increased effectiveness in cellular rejuvenation.
The process of restoring youthful function to aging cells. This is the primary goal of the longevity research discussed, using modified Yamanaka factors discovered by OpenAI's LLM.
A specialized, smaller version of the GPT-4 model developed by OpenAI, trained on protein sequences and biological data to accelerate discoveries in longevity research.
The scientific field focused on extending human lifespan and healthspan. OpenAI's new model represents a significant breakthrough in this area by discovering more effective proteins for cellular rejuvenation.
The macroeconomic period of free money that led to startup overvaluations.
The process of deliberately innovating and making existing products obsolete to drive growth.
A financial information and analytics company whose report is cited as the source for the data on the increasing number of corporate bankruptcies in 2025.
A rising trend in 2025, reaching the highest levels since 2010. The podcast explores the causes, attributing them to the end of the zero-interest-rate policy and the need for market correction.
The trust fund behind Social Security. David Friedberg suggests that equity from government deals should be placed into this fund to help solve its financial crisis.