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All-In's Best Ideas Pitch Competition: 4 Investors Present Their Top Trades Live


Episode Details
Channel

All-In Podcast

Published

6/11/2026

Episode Summary

During a special live segment of the All-In Podcast, co-hosts Chamath Palihapitiya and David Friedberg, joined by guest judge Gavin Baker (filling in for the absent David Sacks), evaluated four compelling investment pitches. First, Aaron Cowen of Suvretta Capital Management pitched MGM Resorts. While primarily known for its Las Vegas casinos and heavy competition with Caesars, the company contains massive hidden upside. This includes an exclusive upcoming casino license in Osaka targeting wealthy gamblers from China, as well as real estate optionality in Dubai. Barry Diller has been aggressively acquiring the stock, creating a robust price floor. Next, Dan Dreyfus of Bornite Capital pitched Talen Energy, a provider of Nuclear Power and Base Load Power operating heavily in the PJM grid. Spotlighting the explosive power demand driven by AI Data Centers, he invoked Sam Zell's strategy of buying below replacement cost and echoed Jensen Huang's warnings regarding impending energy shortages. Big tech firms like Microsoft and Amazon are rapidly locking down grid capacity through Power Purchase Agreements, highlighted by a deal with Constellation Energy to revive the Three Mile Island reactor. The third pitch came from Oleg Nodelman of EcoR1 Capital, who highlighted Aktis Oncology, a highly innovative Biotech firm focusing on Radiopharmaceuticals. Utilizing complex Radioisotopes (specifically Actinium), their therapies execute pinpoint strikes on solid tumors. Heavily backed by Eli Lilly, this complex scientific approach provides a profound moat against generic competition, especially from nations like China which lack access to this specific nuclear supply chain. Finally, Kyle Samani of Multicoin Capital pitched GEODNET, a Crypto infrastructure asset. Operating via the Solana blockchain, it utilizes Tokenization to incentivize a decentralized RTK network, delivering centimeter-level precision that dramatically outperforms legacy GPS. The service is rapidly gaining traction with enterprise clients like John Deere, DJI, and TomTom, powering the next wave of Robotics and Autonomous Driving. Samani previously successfully deployed a similar strategy with the decentralized network Helium.

Investment Ideas
4 ideas
2 high confidence
2 medium confidence

This episode features a live 'Best Ideas' pitch competition where four institutional investors present high-conviction trades. The pitches span diverse sectors including gaming and hospitality, nuclear and base-load energy infrastructure driven by AI data centers, high-moat radiopharmaceuticals, and decentralized physical infrastructure (DePIN) utilizing blockchain incentives.

Portfolio lens: A diversified basket of asymmetric value plays spanning real assets, AI energy infrastructure, high-moat biotechnology, and decentralized physical infrastructure.

Generated with gemini-3.5-flash on 6/25/2026, 6:53:05 PM. For research only. Not financial advice.
MGM Resorts: Hidden Asian Gaming Expansion and Real Estate Optionality
high confidence
Public Equity
Time horizon: long, as the Osaka casino is scheduled to open in 2030 and Dubai legalization is speculative
Thesis

MGM Resorts offers massive asymmetric upside driven by an exclusive upcoming casino license in Osaka, Japan, and real estate optionality in Dubai, with a strong price floor established by Barry Diller's aggressive share accumulation and buyout bid.

Rationale

The pitch highlights that MGM's Osaka casino (opening 2030) targets a massive, untapped Japanese and Chinese gambling market, while its Dubai property has pre-built casino space ready for potential legalization. Barry Diller's 26% stake and $48/share bid, combined with the company buying back half its float, limits downside.

Evidence
  • Barry Diller owns 26% of the company and bid $48 per share.
  • MGM has bought back half of its float in the last 6 years.
  • MGM holds an exclusive license to open a casino in Osaka, Japan, scheduled for 2030.
  • MGM has built a property in Dubai with 300,000 square feet of empty space designed for a casino if gambling is legalized.
Catalysts
  • Progress on the construction and marketing of the Osaka casino ahead of its 2030 opening.
  • Legalization of gambling in Dubai, triggered by Wynn opening a casino in nearby Al Marjan.
  • Barry Diller or the board taking active steps to better monetize the entertainment assets of Vegas properties.
Risks
  • Dubai fails to legalize gambling, leaving the 300,000 square feet of space unmonetized.
  • Caesars previously exited Dubai after waiting unsuccessfully for a license, indicating high regulatory uncertainty.
  • The market continues to discount the Osaka asset due to its long timeline.
Next Diligence
  • Analyze the regulatory timeline and political sentiment for gambling legalization in Dubai.
  • Review MGM's capital expenditure commitments and joint venture structure for the Osaka project.
  • Track Barry Diller's SEC filings regarding his 26% stake and buyout proposal.
MGM Resorts
Barry Diller
Osaka
Dubai
Caesars
Suvretta Capital Management
Aaron Cowen
Talen Energy: Base Load Power Play for AI Data Centers
high confidence
Public Equity
Time horizon: medium to long, aligned with the 10-year grid capacity buildout and data center expansion timeline
Thesis

Talen Energy is a highly undervalued power producer trading below replacement cost that stands to generate massive free cash flow by supplying scarce nuclear and gas base-load power to energy-hungry AI data centers.

Rationale

The pitch argues that AI data centers are driving an unprecedented surge in power demand, forcing tech giants to lock down nuclear capacity via long-term Power Purchase Agreements (PPAs). Talen operates in the tight PJM grid and trades at a massive discount to its replacement value.

Evidence
  • Talen Energy has 2 gigawatts of nuclear power and 6 gigawatts of natural gas base-load power.
  • The company trades at a $25 billion enterprise value compared to an estimated replacement cost of $45 billion.
  • Talen is projected to generate $50 per share of free cash flow by simply running its business and letting its Amazon data center contract roll up.
Catalysts
  • Signing premium behind-the-meter or front-of-the-meter PPAs with hyperscalers.
  • Increases in PJM grid power prices due to supply shortages.
  • Regulatory approval for new power generation capacity and data center collocation.
Risks
  • Regulatory intervention capping electricity prices due to political backlash over rising consumer utility bills.
  • Interest rate hikes compressing valuation multiples on Talen's bond-like PPA cash flows.
  • Competition from alternative power sources like fuel cells, gas turbines, or orbital compute.
Next Diligence
  • Examine Talen's current debt structure and exact replacement cost calculations.
  • Monitor regulatory rulings in the PJM market regarding behind-the-meter data center collocation.
  • Analyze the sensitivity of Talen's FCF projections to interest rate fluctuations.
Talen Energy
PJM
Microsoft
Constellation Energy
Bornite Capital
Dan Dreyfus
Aktis Oncology: High-Moat Radiopharmaceuticals for Solid Tumors
medium confidence
Public Equity
Time horizon: medium, with critical clinical data milestones expected in 2027
Thesis

Aktis Oncology represents a high-conviction biotech play leveraging a proprietary mini-protein platform to deliver precise Actinium-based radiopharmaceuticals to solid tumors, protected by a unique supply-chain moat.

Rationale

The company's radiopharmaceutical approach uses Actinium (sourced from US nuclear waste, making it off-limits to Chinese competitors) to target solid tumors with minimal side effects. It is backed by Eli Lilly and has upcoming clinical readouts in 2027.

Evidence
  • Aktis Oncology (AKTS) recently went public with a $300 million IPO, backstopped by a $100 million order from Eli Lilly.
  • The company's lead programs target Nectin 4 and B7H3, with initial clinical data expected in 2027.
  • The Actinium payload is manufactured from Radium 233, a legacy waste product of US nuclear programs, creating a supply chain moat that is inaccessible to China.
Catalysts
  • Initial clinical trial data readouts for Nectin 4 and B7H3 programs in 2027.
  • Potential acquisition bid by backing pharma partners like Eli Lilly or Novartis.
  • Expansion of the mini-protein platform to target other solid tumors.
Risks
  • Clinical trial failure or safety concerns in early-stage programs.
  • Dilution from secondary equity offerings to fund ongoing R&D.
  • Competition from alternative solid tumor modalities like antibody-drug conjugates.
Next Diligence
  • Review the clinical trial design and patient enrollment status for Aktis' Nectin 4 and B7H3 programs.
  • Investigate the global supply chain and manufacturing constraints of Actinium-225.
  • Assess competitive solid tumor therapies currently in Phase I/II trials.
Aktis Oncology
Eli Lilly
Actinium
EcoR1 Capital
Oleg Nodelman
GEODNET: Decentralized RTK Network for Autonomous Systems
medium confidence
Technology Watchlist
Time horizon: medium, as commercial robotics and autonomous driving scale up over the next 3-5 years
Thesis

GEODNET is a highly capital-efficient, decentralized physical infrastructure network (DePIN) poised to monopolize high-precision RTK geolocation for robotics, drones, and autonomous driving.

Rationale

By using token incentives on the Solana blockchain, GEODNET rapidly built the world's largest RTK network at a fraction of the cost of legacy competitors. It uses 80% of its revenues to buy back its native GEOD token on the open market, creating a direct value accrual mechanism.

Evidence
  • GEODNET provides centimeter-level precision (RTK) compared to standard GPS (2-meter precision).
  • The network has over 22,000 nodes deployed across 150 countries, built via decentralized crypto incentives.
  • The project has crossed $11 million in annualized run rate, with 80% of revenue used to buy back GEOD tokens on the open market.
Catalysts
  • Increased adoption of robotic lawnmowers, agricultural drones, and autonomous vehicles.
  • Continued token buybacks visible on the Solana blockchain.
  • Regulatory clarity via legislation like the Clarity Act.
Risks
  • Low token liquidity making it difficult for large institutional positioning.
  • Regulatory/securities law challenges regarding the revenue-share token structure.
  • Disruption by low-Earth-orbit (LEO) satellite constellations providing sub-centimeter resolution.
Next Diligence
  • Verify the token buyback transactions and smart contract addresses on the Solana blockchain.
  • Evaluate the technical feasibility and cost of LEO satellite constellations replacing ground-based RTK networks.
  • Analyze GEODNET's customer concentration and contract terms with major partners like TomTom and DJI.
GEODNET
Solana
John Deere
DJI
TomTom
Multicoin Capital
Kyle Samani
Watchlist
  • MGM Resorts stock price
  • Talen Energy free cash flow metrics
  • Aktis Oncology (AKTS) clinical trial updates
  • GEOD token buyback volume on Solana
  • PJM grid power prices
  • Barry Diller's MGM ownership percentage
Open Questions
  • Will regulatory bodies block behind-the-meter nuclear power collocation for AI data centers?
  • Can LEO satellite constellations achieve centimeter-level RTK precision at a lower cost than ground stations?
  • Will Dubai legalize gambling, and what is the timeline for Wynn's competing casino in Al Marjan?
  • How will rising interest rates impact the valuation multiples of long-term power purchase agreements (PPAs)?
Key Topics & People

CEO of Nvidia, heavily involved in the global AI hardware market.

China
China
PoliticalEntity

The geopolitical and technological competitor to the US in artificial intelligence.

Investor and podcast guest discussing space, IPOs, and technology markets.

Investor and podcast host offering insights on geopolitical conflicts, US policy, and politics.

Investor and podcast host analyzing AI infrastructure, politics, and markets.

Microsoft
Microsoft
Organization

A major technology company that acquired Skype from an investor group after eBay sold its majority stake.

Amazon
Amazon
Organization

The dominant e-commerce and supply chain leader that served as the primary competitor for Chewy and eBay.

Host of the All-In Podcast conducting the interview with Ryan Cohen.

All-In Podcast
Organization

The podcast hosting the interview with GameStop CEO Ryan Cohen.

Investor running Suvretta Capital Management who pitches MGM Resorts.

MGM Resorts
Organization

A casino and entertainment company with highly valuable hidden asset opportunities in Japan and Dubai.

Caesars
Caesars
Organization

A major casino competitor to MGM Resorts.

A $4 billion investment firm run by Aaron Cowen.

Dubai
Dubai
Location

A city where MGM has a property containing empty space potentially designated for a future casino.

Bornite Capital
Organization

Investment fund represented by Dan Dreyfus at the pitch competition.

Osaka
Osaka
Location

A Japanese prefecture where MGM Resorts has an exclusive license to open a massive new casino.

Talen Energy
Organization

A power producer possessing extensive nuclear and natural gas baseload power assets.

PJM
Location

A regional power grid covering Pennsylvania, Jersey, and Maryland with skyrocketing projected energy needs.

Constant, reliable power generation needed to sustain the immense continuous energy demands of infrastructure.

A power company that struck a deal with Microsoft to restart a historic nuclear reactor.

Sam Zell
Sam Zell
Person

A legendary investor whose strategy of buying hard assets below replacement cost was referenced during the Talen Energy pitch.

Long-term contracts under which hyperscalers buy electricity from power producers at fixed premium prices.

A historic nuclear power plant being restarted to provide electricity for Microsoft's AI operations.

EcoR1 Capital
Organization

A San Francisco-based value-oriented biotech fund founded by Oleg Nodelman.

Founder of EcoR1 Capital pitching biotech company Aktis Oncology.

Radioisotopes
Technology

Radioactive elements utilized in therapies to destroy cancer cells.

Medical drugs containing radioactive isotopes used for precision targeted cancer treatments.

Aktis Oncology
Organization

A radiopharmaceutical company developing mini-protein targeted cancer therapies.

Actinium
ScientificConcept

The specific powerful radioisotope used by Aktis Oncology, sourced uniquely from legacy US programs.

GEODNET
Organization

A decentralized network utilizing cryptocurrency to incentivize the deployment of highly precise RTK base stations.

RTK
Technology

Real-Time Kinematics, a technology providing sub-centimeter geolocation accuracy superior to GPS.

John Deere
John Deere
Organization

An agriculture machinery company using the GEODNET network for autonomous spraying and farming systems.

GPS
Technology

Legacy Global Positioning System technology that provides basic, but comparatively less precise, geolocation.

TomTom
TomTom
Organization

A mapping and navigation company utilizing GEODNET to improve its systems for autonomous vehicles.

Helium
Helium
Topic

A highly successful decentralized infrastructure project previously backed by Multicoin Capital.

A mobility sector dependent on advanced geolocation mapping like RTK for navigation.

Robotics
Robotics
Technology

An industry relying on precision data provided by networks like GEODNET for autonomous operation.

DJI
DJI
Organization

The world's largest drone manufacturer, cited as a prominent customer of the GEODNET network.

The system of using crypto tokens to economically incentivize the building of physical decentralized networks.

Solana
Organization

The high-speed blockchain network upon which the GEODNET token trades.

Crypto
Technology

The digital asset and blockchain space forming the foundation of GEODNET's economic model.

Multicoin Capital
Organization

A crypto-focused investment firm founded by Kyle Samani.

Founder of Multicoin Capital who pitches the decentralized infrastructure token GEODNET.

Eli Lilly
Eli Lilly
Organization

Major pharmaceutical company that heavily backed the IPO of Aktis Oncology.

Biotech
Topic

The sector of medicine and science focused on developing biological and chemical therapies.

Specialized facilities designed for artificial intelligence workloads that demand massive amounts of electricity.

Nuclear Power
Technology

A highly reliable, constant energy source crucial for powering next-generation data centers.

Investor from Bornite Capital who pitches Talen Energy.

Legendary media executive aggressively bidding for and buying shares of MGM Resorts.

Las Vegas
Las Vegas
Location

The primary operational location for MGM Resorts' domestic casino assets.