Arc Institute

Extracted Attributes

• Type

  Nonprofit biomedical research organization

• Founded

  2021

• Mission

  Fostering unrestricted, curiosity-driven research to address complex diseases; accelerating scientific progress and translating discoveries into patient impact

• Headquarters

  Palo Alto, California

• Research Focus

  Biomedical science and technology, complex human diseases, fundamental biological mechanisms, new technologies, therapeutic concepts

• Initial Endowment

  $650 million

• Executive Director

  Silvana Konermann

• Personnel Goal (Phase 1)

  150-350 scientific personnel (10-15 Core Investigators, each with 10-20 trainees/researchers/engineers, plus 5 Technology Centers)

Timeline

• Arc Institute was founded. (Source: Web Search)

  2021-XX-XX

• Patrick Collison outlined the mission of the Arc Institute and announced the release of Evo2, a large foundation model for biology. (Source: Related Documents)

  202X-XX-XX

• Arc Institute launched an open benchmarking competition to evaluate virtual cell models. (Source: Web Search)

  202X-XX-XX

Arc Institute

Arc Institute is a nonprofit biomedical research organization based in Palo Alto, California. It was co-founded by Stanford University biochemistry professor Silvana Konermann, UC Berkeley bioengineering professor Patrick Hsu, and Stripe CEO Patrick Collison, with Konermann as its inaugural executive director. The institute operates in partnership with three San Francisco Bay Area research universities—Stanford, UC Berkeley, and UCSF.

Web Search Results

• Arc Institute - CB Insights

  Arc Institute is a nonprofit research organization focused on curiosity-driven biomedical science and technology. The institute provides multi-year funding for scientists to pursue research without the need for external grants and invests in the development of experimental and computational technological tools. Arc Institute primarily serves the biomedical research and healthcare sectors by aiming to accelerate scientific progress and translate discoveries into patient impact. It was founded in [...] Arc Institute was founded in 2021. Where is Arc Institute's headquarters? Arc Institute's headquarters is located at 3160 Porter Drive, Palo Alto. Loading... Loading... CB Insights Follow Us On Social Twitter Linkedin Facebook ### About ### How We Help ### What We Offer ### Popular Research Copyright 2025 CB Information Services, Inc. All rights reserved. [...] In this episode of GEN's Touching Base, Merck acquires Verona Pharma for $10 billion. Additionally, Arc Institute launches an open benchmarking competition to evaluate virtual cell models while AAV-OTOF gene therapy shows promise in restoring hearing loss. The post Merck Acquires Verona, Virtual Cell Challenge, Gene Therapy Restores Hearing appeared first on GEN - Genetic Engineering and Biotechnology News. ### Arc Institute Frequently Asked Questions (FAQ) When was Arc Institute founded?

• Arc Institute - Wikipedia

  Arc Institute is a nonprofit biomedical research organization based in Palo Alto, California. It was co-founded by Stanford University biochemistry professor Silvana Konermann, UC Berkeley bioengineering professor Patrick Hsu, and Stripe CEO Patrick Collison, with Konermann as its inaugural executive director. The institute operates in partnership with three San Francisco Bay Area research universities—Stanford, UC Berkeley, and UCSF. ## History [...] Arc Institute was founded in 2021 to provide scientists with research opportunities without the need for external grant applications. This followed a collaboration between Konermann, Hsu, and Collison on Fast Grants during the COVID-19 pandemic. [...] Arc Institute was launched with an initial endowment of $650 million. Founding donors include Ethereum creator Vitalik Buterin, Stripe co-founders Patrick Collison and John Collison, angel investor Ron Conway, Color Genomics co-founder Elad Gil, Cue "Cue (search engine)") co-founder Daniel Gross "Daniel Gross (businessman)"), Facebook and Asana co-founder Dustin Moskovitz, Open Philanthropy chair Cari Tuna, General Catalyst CEO Hemant Taneja, and Jane Street Capital executives. Silvana

• About | Arc Institute

  Arc is influenced and inspired by the success of many existing institutional experiments, including HHMI’s Janelia Research Campus, the Broad Institute, the Salk Institute, CZ Biohub, the Crick Institute, the Max Planck Society, and many others. The basic thesis behind Arc is that there are a couple of ingredients that haven’t been combined before: We hope that Arc contributes usefully to our understanding of the space of effective configurations for organizing scientific research. [...] The Institute‘s growth through 2025 is gradual, with the goal of building a culture and organization that scales. Phase 1 of the institute involves hiring 10–15 Core Investigators, each of whom may employ 10–20 trainees, researchers, or engineers. Our 5 Technology Centers will ultimately be of similar size, for a total headcount of approximately 150–350 scientific personnel. [...] #### How much funding is behind Arc? Arc’s donors are contributing more than $650M to the Institute to allow it to fully sustain scientists and their research for renewable eight-year terms. #### What are the roles of the founders? Silvana Konermann is a cofounder of Arc, a Core Investigator, and serves as the Institute’s Executive Director. Patrick Hsu is a cofounder of Arc and a Core Investigator. He leads the development of certain Technology Centers and the Translation Program.

• Arc Institute Programs

  Arc Faculty and Fellows # Arc Institute Programs ### As part of our mission to understand and treat complex human diseases, the Arc Institute is excited to continue to grow our scientific community across our investigator programs. #### Core Investigators #### Science Fellows #### Innovation Investigators & Ignite Awardees ## Sign up to be notified of updates and news about our Programs. ## Life as an Investigator at Arc [...] All Core Investigator and Science Fellow labs are located in Arc‘s brand, new 100,000 sqft headquarters. Designed with scientists in mind, the offices and labs feature bright, sunlit spaces and state-of-the-art equipment. Innovation Investigators also have access to flex space in our building. #### Equipment & Technology [...] All Arc investigators receive unrestricted, flexible funding to pursue their most important ideas - with complete freedom to study fundamental biological mechanisms, develop new technologies, or innovate on therapeutic concepts. We encourage interdisciplinary collaboration, curiosity-driven exploration, and goal-oriented research. Professor Hani Goodarzi in lab ### Arc‘s robust infrastructure of resources enables our Investigators to advance ambitious, long-term research agendas.

• Arc Institute

  rewired in response to changing environmental conditions. Here, we developed a framework for mapping context-specific genetic interactions, enabling us to measure the plasticity of human genetic architecture upon environmental challenge for ∼250,000 interactions, using cell cycle interruption, genotoxic perturbation, and nutrient deprivation as archetypes. We discover large-scale rewiring of human gene relationships across conditions, highlighted by dramatic shifts in the functional connections [...] Abstract: Genomic rearrangements, encompassing mutational changes in the genome such as insertions, deletions, or inversions, are essential for genetic diversity. These rearrangements are typically orchestrated by enzymes involved in fundamental DNA repair processes such as homologous recombination or in the transposition of foreign genetic material by viruses and mobile genetic elements (MGEs). We report that IS110 insertion sequences, a family of minimal and autonomous MGEs, express a [...] © Arc Institute