Open Evidence
An AI company focused on providing verifiable medical and healthcare information.
First Mentioned
7/23/2026, 6:05:51 AM
Last Updated
7/23/2026, 6:11:25 AM
Research Retrieved
7/23/2026, 6:11:25 AM
Summary
Open Evidence (OpenEvidence) is an American artificial intelligence company founded by Daniel Nadler and headquartered in Miami, Florida. The company develops an AI-powered medical search engine and clinical decision support platform designed to assist healthcare professionals by aggregating, synthesizing, and citing peer-reviewed medical literature. Open Evidence maintains official AI partnerships with leading medical bodies and journals including The New England Journal of Medicine (NEJM), JAMA Network, NCCN, and Cochrane. In the healthcare sector, its diagnostic tools contribute to clinical decision support and self-directed patient care. By January 2026, the company reached a valuation of $12 billion following multiple funding rounds.
Referenced in 1 Document
Research Data
Extracted Attributes
Founder
Daniel Nadler
Product
AI-powered clinical decision support platform and medical search engine
Industry
Artificial Intelligence, Healthcare
Valuation
$12 billion USD (as of January 2026)
Headquarters
Miami, Florida, United States
Timeline
- Open Evidence was founded by Daniel Nadler and selected to participate in a Mayo Clinic Platform accelerator. (Source: undefined)
2021-11-01
- Open Evidence launched its medical AI platform in collaboration with the Mayo Clinic Platform. (Source: undefined)
2023-01-01
- Open Evidence became HIPAA-compliant for covered entities handling Protected Health Information (PHI). (Source: undefined)
2025-04-25
- Open Evidence achieved a company valuation of $12 billion following several funding rounds. (Source: undefined)
2026-01-01
Wikipedia
View on WikipediaOpenEvidence
OpenEvidence is an American artificial intelligence company that develops a medical search engine used by healthcare professionals for clinical decision support. The company was founded in 2022 by entrepreneur Daniel Nadler and is headquartered in Miami, Florida. As of January 2026, the company is valued at $12 billion, following several funding rounds.
Web Search Results
- OpenEvidence - PMC - NIH
OpenEvidence, an artificial intelligence (AI) assisted medical platform, was founded by Dr. Daniel Nadler. OpenEvidence was developed in collaboration with a team of physicians and computer scientists with a mission to offer reliable, unbiased and validated medical information to healthcare professionals at no cost . OpenEvidence (OE) is available through its website ( and features partnerships with prominent journals such as NEJM, JAMA and Lancet to ensure content of the highest quality. Since its launch in 2023, in collaboration with the Mayo Clinic Platform, it remains an essential and evident resource in the medical field. OE leverages natural language processing (NPL) to streamline research efforts, and deliver comprehensive evidence-based insights into diagnosis, treatment options, [...] ## FEATURES OpenEvidence serves as a fast and reliable tool for answering clinical questions, such as inquiries regarding treatment options, drug dosing, drug side effects, drug interactions, labs to consider, alternative treatments, and updated guidelines. It can also handle more complex tasks, such as preparing for mock exams, conducting research on a specific topic, finding evidence, and developing appropriate treatment plans. A new feature of OE includes email notification, alerting users to updates on previously asked questions, and ensuring continuous access to the latest information. Additionally OE is available in multiple languages, further expanding its accessibility. [...] Unlike other medical websites and databases that offer pre-prepared information, OE allows users to directly request evidence without needing to spend hours sifting through articles. OE is an excellent resource for physicians at the point of care; it assists physicians to quickly obtain answers from the peer-reviewed materials, utilizing current research that is reliable for medical practice. OE has implemented specific strategies to incorporate evidence-based and peer-reviewed materials from reputable journals, such as the Lancet, JAMA, and the New England Journal of Medicine.
- About
Cochrane Cochrane An Official AI Partner of Cochrane Systematic Reviews. OpenEvidence content includes figures, tables, multimedia and full-text from Cochrane Systematic Reviews. Our mission is to help doctors save lives and improve patient care. This year, more than 100 million Americans will be treated by a clinician using OpenEvidence. As a product, OpenEvidence is an AI copilot for doctors that helps them make high-stakes decisions at the point of care. OpenEvidence is the most widely used medical AI among verified U.S. clinicians. To date, we have supported over 200 million AI-powered clinical consultations from U.S. doctors and other frontline clinicians. [...] OpenEvidence has signed content agreements withNEJM, JAMA, NCCN, Wiley, Cochrane, and more. # OpenEvidence is the leading medical information platform. An Official AI Partner of The New England Journal of Medicine. OpenEvidence content includes figures, tables, multimedia and full-text clinical findings from The New England Journal of Medicine. JAMA Network JAMA Network An Official AI Partner of JAMA and the JAMA Network specialty journals. OpenEvidence content includes figures, tables, multimedia and full-text clinical findings from JAMA and the JAMA Network specialty journals. NCCN NCCN An Official AI Collaboration with the National Comprehensive Cancer Network (NCCN). OpenEvidence content includesNCCN Guidelines® Treatment Algorithms. Cochrane Cochrane
- What is Open Evidence and Should I Incorporate This Into My Practice?
Sinai EM # What is Open Evidence and Should I Incorporate This Into My Practice? Will Artificial Intelligence take over my job? Not likely in the immediate future! Can it help me right now to make more evidence based decisions in my daily practice? Possibly! Now that artificial intelligence (AI) tools have become ubiquitous in our society, you may be asking yourself how you can use these tools to make your life easier. In this short pearl, we will explore one tool, Open Evidence, and how you may use it to help answer some questions on your next shift. Open Evidence is an AI powered web-based platform that, much like ChatGPT, has the ability to aggregate and synthesize literature and present information in a way that helps clinicians make evidence-based decisions. [...] To be very clear… Open Evidence is an experimental technology that CANNOT fully substitute your clinical judgement and assessment of current guidelines/literature when making clinical decisions. According to the Mount Sinai Levy Library: “OpenEvidence is one source, and as an experimental learning tool, should not be the only source of information you consult. It’s crucial to check what the original references say and document the AI-generated information… All AI systems may make errors, and without knowing which sources it is consulting, you should continue to compare outputs with trusted sources to ensure you have obtained the highest level of evidence for your clinical questions.” Now that we have that out of the way….
- OpenEvidence App - App Store
Clinical Decision Support & Medical Search Engine for Healthcare Professionals (NPI Required). OpenEvidence is trusted by hundreds of thousands of verified healthcare professionals to support high-stakes clinical decisions at the point of care with answers that are sourced, cited, and grounded in peer-reviewed medical literature. OpenEvidence is the fastest-growing and most widely-used clinical decision support platform in the world–used daily, on average, by over 40% of physicians in the United States, spanning more than 10,000 hospitals and medical centers nationwide. Now sourcing from over 300+ medical journals, as well as the FDA and CDC. OpenEvidence is an official AI partner of The New England Journal of Medicine and the Journal of American Medical Association (and their 11
- AI in Teaching and Learning Blog - Levy Library Guides at Icahn School of Medicine at Mount Sinai
OpenEvidence is an experimental technology demonstrator service. It is not meant to provide medical advice, diagnosis or treatment. Users must assess the information they obtain from OpenEvidence. Providers must acknowledge their obligation to adhere to all laws and professional standards applicable to their field of practice of medicine or other relevant health profession ( [...] Skip to Main Content School Header Page Showing of Results # OpenEvidence as Learning Tool Mia Bolton Artificial Intelligence and Human Health Introduction to OpenEvidence OpenEvidence is an AI-powered platform that aggregates, synthesizes, and visualizes peer reviewed medical literature in a format intended to be easily understood and support healthcare professionals in learning and making evidence-based decisions ( Daniel Nadler, PhD founded Kensho Technologies while immersed in his studies. Nadler founded OpenEvidence in November 2021 and was selected to participate in a Mayo Clinic Platform accelerator. As of October 2021, more than 10,000 clinicians have registered for accounts ( [...] OpenEvidence is HIPAA-compliant as of April 25, 2025 ( “Covered entities” who chose to input PHI on OpenEvidence agree that such information will be handled in accordance with their Business Associate Agreement. All OpenEvidence users are responsible for ensuring that inputs comply with laws, including HIPAA and other privacy regulations ( Agreeing to the Terms of Use is assumed by the user at the time they engage with the tool ( OpenEvidence may collect data from the prompts asked and the interactions had with the service. They claim this data is collected to better understand customers’ behavior and use of the product. Their terms state they may disclose, distribute, transfer, and sell non-personal information and customer usage data for any purpose including commercial uses. Data in
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Inception Date
1/1/2013