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Natera

Organization

A highly successful genetic diagnostics company in Sequoia's portfolio, which grew from a $1 million seed investment to a $22 billion market capitalization, showcasing the potential of diagnostics as a VC investment.


First Mentioned

10/10/2025, 3:08:05 AM

Last Updated

10/10/2025, 3:10:56 AM

Research Retrieved

10/10/2025, 3:10:56 AM

Summary

Natera, Inc. is a leading clinical genetic testing company, founded in 2004 by Matthew Rabinowitz and Jonathan Sheena, specializing in non-invasive, cell-free DNA (cfDNA) testing technology. Headquartered in Austin, Texas, with CAP-accredited and CLIA-certified laboratories in San Carlos, California, and Austin, it focuses on women's health, cancer, and organ health. The company utilizes proprietary technology combining advanced molecular biology and bioinformatics software for highly sensitive detection. Natera has achieved significant success in the biotech sector, notably backed by investors like Sequoia Capital, despite Sequoia's acknowledged limited in-house scientific expertise in the field.

Referenced in 1 Document
Research Data
Extracted Attributes
  • Country

    United States

  • Founded

    2004-01-01

  • Industry

    Clinical genetic testing, Biotechnology Research

  • Traded As

    Nasdaq: NTRA, Russell 1000 component

  • Focus Areas

    Women's health, cancer, organ health

  • Former Name

    Gene Security Network, Inc. (2004-2012)

  • Company Name

    Natera, Inc.

  • Company Type

    Public

  • Headquarters

    Austin, Texas, U.S.

  • Accreditations

    CAP-accredited laboratories, CLIA-certified laboratories, ISO 13485-certified

  • Revenue (2022)

    US$797 million

  • Specialization

    Non-invasive, cell-free DNA (cfDNA) testing technology

  • Core Technology

    Proprietary molecular biology techniques with bioinformatics software

  • Laboratory Locations

    San Carlos, California, U.S.; Austin, Texas, U.S.

  • Employees (as of 2024)

    4,434

  • Operating Income (2022)

    US$-541 million

  • Market Capitalization (as of 2025-06-30)

    US$18.4 billion

Timeline
  • Natera was founded as Gene Security Network by Matthew Rabinowitz and Jonathan Sheena. (Source: Wikidata, Web Search)

    2004-01-01

  • Natera launched its first product, the Spectrum preimplantation genetic test. (Source: Web Search)

    2009

  • The company introduced the Anora miscarriage (POC) test. (Source: Web Search)

    2010

  • Natera launched the Horizon advanced carrier screening test. (Source: Web Search)

    2012

  • The company was renamed from Gene Security Network, Inc. to Natera. (Source: Web Search)

    2012

  • Natera launched the Panorama non-invasive prenatal test (NIPT). (Source: Web Search)

    2013

  • Natera reported US$797 million in revenue and US$-541 million in operating income. (Source: Web Search)

    2022

  • Natera employed 4,434 people. (Source: Web Search)

    2024

  • Natera had a market capitalization of US$18.4 billion. (Source: Web Search)

    2025-06-30

Natera

Natera, Inc. is a clinical genetic testing company based in Austin, Texas that specializes in non-invasive, cell-free DNA (cfDNA) testing technology, with a focus on women’s health, cancer, and organ health. Natera’s proprietary technology combines novel molecular biology techniques with a suite of bioinformatics software that allows detection down to a single molecule in a tube of blood. Natera operates CAP-accredited laboratories certified under the Clinical Laboratory Improvement Amendments (CLIA) in San Carlos, California and Austin, Texas.

Web Search Results
  • Natera - Wikipedia

    Natera, Inc. is a clinical genetic testing company based in Austin, Texas that specializes in non-invasive, cell-free DNA (cfDNA) testing technology, with a focus on women’s health, cancer, and organ health. Natera’s proprietary technology combines novel molecular biology techniques with a suite of bioinformatics software that allows detection down to a single molecule in a tube of blood. Natera operates CAP-accredited laboratories certified under the Clinical Laboratory Improvement Amendments [...] ## History [edit] Natera (previously Gene Security Network) was founded by Matthew Rabinowitz and Jonathan Sheena in 2004. Natera launched its first product, the Spectrum preimplantation genetic test, in 2009. In 2010, the company introduced the Anora miscarriage (POC) test. Natera's advanced carrier screening test, Horizon, launched in 2012. The following year, 2013, Natera launched the Panorama non-invasive prenatal test (NIPT). [...] | Formerly | Gene Security Network, Inc. (2004–2012) | | Company type | Public | | Traded as | Nasdaq: NTRA Russell 1000 component | | Industry | Genetic testing | | Founded | 2004; 21 years ago (2004) | | Founders | Matthew Rabinowitz Jonathan Sheena | | Headquarters | Austin, Texas, U.S. | | Key people | Steve Chapman (CEO) Rishi Kacker (CTO) Matthew Rabinowitz (executive chairman) | | Revenue | US$797 million (2022) | | Operating income | US$−541 million (2022) |

  • Natera | LinkedIn

    Natera™ is a global leader in cell-free DNA and genetic testing, dedicated to oncology, women’s health, and organ health. We aim to make personalized genetic testing and diagnostics part of the standard of care to protect health and inform earlier, more targeted interventions that help lead to longer, healthier lives. Natera’s tests are validated by more than 250 peer-reviewed publications that demonstrate high accuracy. Natera operates ISO 13485-certified and CAP-accredited laboratories [...] # Natera We are a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women’s health, and organ health. Biotechnology Research • Austin, Texas • 198,280 followers • 5,001-10,000 employees [...] hiring team. Natera takes cyber crimes seriously, and will collaborate with law enforcement authorities to prosecute any related cyber crimes.

  • Natera vs. Myriad: How do these genetic testing services measure up?

    ``` ### How Natera works Natera is a U.S.-based company specializing in DNA testing, with services available in many countries. It offers screening for: Cancer patients looking for insights into their condition and treatment options Pregnant individuals assessing potential risks during pregnancy and their baby’s health Prospective parents who want to understand their chances of passing on genetic conditions Organ transplant recipients who need to monitor their new organ’s health [...] Natera’s tests rely on cell-free DNA (cfDNA), the genetic material that enters the bloodstream when cells break down. Using your blood sample, Natera's tests measure cfDNA levels to detect patterns linked to various conditions, including cancer.

  • Natera 2025 Company Profile: Stock Performance & Earnings

    Natera Inc is a diagnostic and research company with proprietary molecular and bioinformatics technology. The company's key product offerings include its Panorama Non-Invasive Prenatal Test (NIPT) which screens for chromosomal abnormalities of a fetus as well as in twin pregnancies, typically with a blood draw from the mother, Horizon Carrier Screening (HCS) to determine carrier status for a large number of severe genetic diseases that could be passed on to the carrier's children, Signatera [...] | Stock Price | Previous Close | 52 wk Range | Market Cap | Shares | Average Volume | EPS | --- --- --- | $134.58 | $133.66 | $92.14 - $183.00 | $18.4B | 137M | 1.34M | -$1.47 | ## Natera Financials Summary As of 30-Jun-2025, Natera has a trailing 12-month revenue of $1.96B. [...] Natera Inc is a diagnostic and research company with proprietary molecular and bioinformatics technology. The company's Laboratory Services (Healthcare) Austin, TX 4,434 As of 2024 ## San Francisco, CA ## Salt Lake City, UT Add Comparison PitchBook’s comparison feature gives you a side-by-side look at key metrics for similar companies. Personalize which data points you want to see and create visualizations instantly. Request a free trial ## Natera Competitors (12)

  • About Us - Natera

    Skip navigation Pay Bill Portals # DNA is in our blood Natera™ is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women’s health, and organ health. We aim to make personalized genetic testing and diagnostics part of the standard of care to protect health and inform earlier, more targeted interventions that help lead to longer, healthier lives. ## Innovating with Integrity ## Validation and Evidence [...] ## Advancing the leading edge of molecular diagnostics ## Natera was founded from a personal mission to help change standards of care. #### MATTHEW RABINOWITZ Founder of Natera In 2004, my sister gave birth to a son with a severe genetic condition. He passed away six days after birth. It was a devastating experience for our entire family. I founded Natera because I believe all families deserve access to technologies that offer early detection of genetic disease. [...] ## Acting with Care for the Future We are committed to reducing the environmental impact of our business. Natera complies with all applicable local, state, and federal environmental regulations and we conduct regular reviews to ensure our supplier partners and contractors do the same. As part of our sustainability program, we are committed to reducing the environmental impact of our laboratories, our corporate offices, our supply chain, and our waste operations.

Natera, Inc. is a clinical genetic testing company based in Austin, Texas that specializes in non-invasive, cell-free DNA (cfDNA) testing technology, with a focus on women’s health, cancer, and organ health. Natera’s proprietary technology combines novel molecular biology techniques with a suite of bioinformatics software that allows detection down to a single molecule in a tube of blood. Natera operates CAP-accredited laboratories certified under the Clinical Laboratory Improvement Amendments (CLIA) in San Carlos, California and Austin, Texas.

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Location Data

Natera, Uribarri Kuartango, Kuartango, Añanako kuadrilla/Cuadrilla de Añana, Araba/Álava, Euskadi, 01439, España

locality

Coordinates: 42.8568030, -2.9062806

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