autoimmunity

Extracted Attributes

• Field

  Immunology

• Mechanism

  Immune system attacks own healthy cells, tissues, and normal bodily components

• Characteristic

  Presence of antibodies or T cells that react with self-protein

• Common Treatment

  Steroid treatments

• Normal Occurrence

  Present in all individuals, even in normal health state

• Consequence if pathological

  Autoimmune diseases if self-reactivity leads to tissue damage

Timeline

• A scientific theory involving autoimmunity and the folate receptor was explored in discussions regarding a potential link between Autism and Tylenol (acetaminophen) use during pregnancy, referencing a paper by Andrea Bakarelli, during an All-In Podcast episode. (Source: Related Documents)

  2023-10-20

Autoimmunity

In immunology, autoimmunity is the system of immune responses of an organism against its own healthy cells, tissues and other normal body constituents. Any disease resulting from this type of immune response is termed an "autoimmune disease". Prominent examples include celiac disease, diabetes mellitus type 1, Henoch–Schönlein purpura, systemic lupus erythematosus, Sjögren syndrome, eosinophilic granulomatosis with polyangiitis, Hashimoto's thyroiditis, Graves' disease, idiopathic thrombocytopenic purpura, Addison's disease, rheumatoid arthritis, ankylosing spondylitis, polymyositis, dermatomyositis, and multiple sclerosis. Autoimmune diseases are very often treated with steroids. Autoimmunity means presence of antibodies or T cells that react with self-protein and is present in all individuals, even in normal health state. It causes autoimmune diseases if self-reactivity can lead to tissue damage.

Web Search Results

• Autoimmune Diseases: Types, Symptoms & Treatments

  There’s no cure for autoimmune diseases, but your healthcare provider will help you find treatments that manage the symptoms you experience. ### What are autoimmune disease symptoms? We know your immune system mistakenly damaging your body instead of protecting it causes the symptoms of an autoimmune disease you experience. Some common treatments to manage autoimmune disease symptoms include: Conditions like multiple sclerosis and myositis are more likely to be fatal than many autoimmune diseases, but that doesn’t mean they always are. If you’ve already been diagnosed with an autoimmune disease, tell your provider if it feels like your treatments aren’t working as well as they used to or if the symptoms are recurring more often.

• Definition of Autoimmunity & Autoimmune Disease

  Autoimmune diseases develop when the auto-reactive B lymphocytes (autoantibodies) and T lymphocytes described above cause a pathological and/or functional damage to the organ/tissue containing the target autoantigen(s). B cells also secrete antibodies that when directed against self components are called autoantibodies (as found in patients with autoimmune diseases). A normal component of the patient, such as a protein or a protein-nucleic acid complex, that becomes recognized by the patient's own antibodies and/or T lymphocytes during an autoimmune disease. The type of antibodies that recognize antigens of the patient, always present in autoimmune diseases and sometimes causing them. An autoimmune disease predominantly targeting the thyroid gland, and mediated by autoantibodies that bind to and stimulate a receptor expressed on thyroid cells called TSH receptor.

• Autoimmune Disease Symptoms - MedlinePlus

  Autoimmune Diseases # Autoimmune Diseases ### What are autoimmune diseases? ### What are the symptoms of autoimmune diseases? To help your doctor find out if an autoimmune disease is causing your symptoms,: * Understanding Autoimmune Diseases (National Institute of Arthritis and Musculoskeletal and Skin Diseases) Also in Spanish * Understanding Autoimmune Diseases: When Your Body Turns Against You (National Institutes of Health) Also in Spanish * Autoimmune Hepatitis (National Institute of Diabetes and Digestive and Kidney Diseases) Also in Spanish * Autoimmune Lymphoproliferative Syndrome (ALPS) (National Institute of Allergy and Infectious Diseases) * ClinicalTrials.gov: Autoimmune Diseases (National Institutes of Health) * National Institute of Arthritis and Musculoskeletal and Skin Diseases Also in Spanish

• Risk Factors | Global Autoimmune Institute

  7 Risk Factors for Autoimmune Disease · 1. Your Sex · 2. Genetics · 3. Having An Autoimmune Disease · 4. Obesity · 5. Smoking and Exposure to Toxic Agents · 6.

• Autoimmunity and Triggers - American College of Rheumatology

  It’s clear that there are factors, beyond a person’s genetic makeup, that contribute to a person’s chance of developing an autoimmune disease. Some infections may increase the chance of developing an autoimmune disease. Medications have also been implicated in the development of autoimmune disease. Again, it is important to understand that while genetics, infections, smoking, and certain medications are associated with risk, none have been definitively shown to cause autoimmune disease. The American College of Rheumatology encourages you to meet with your care team regularly to ensure you manage your disease and continue to live a healthy life. At NYU, she saw a diverse group of patients with complicated autoimmune diseases and contributed to the education of fellows and faculty.

• Instance Of

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