IVF (In-Vitro Fertilization)

Extracted Attributes

• Type

  Assisted Reproductive Technology (ART)

• Limitations

  Financial cost, Age, Country-specific bans or regulations

• Primary Purpose

  Treat infertility

• Future Potential

  Creation of viable eggs from skin cells using Yamanaka factors and Stem Cell Technology

• Process Overview

  Monitoring and stimulating ovulation, egg retrieval, in vitro fertilization with sperm, embryo culture (2-6 days), embryo transfer to uterus

• Additional Purposes

  Enable gestational surrogacy, Prevent transmission of genetic disorders (with pre-implantation genetic testing)

• First Successful Birth

  Louise Brown

• Cautionary Finding (2019)

  Avoidance of certain adjuncts (e.g., DHEA, testosterone, aspirin, antioxidants) until more evidence of safety and effectiveness

• Global Births (as of 2023)

  Estimated 12 million children via IVF and similar ARTs

• Location of First Procedure

  Dr Kershaw's Cottage Hospital, Royton, Oldham, England

Timeline

• Louise Brown, the first child successfully born via IVF, was born as a result of natural-cycle IVF at Dr Kershaw's Cottage Hospital in Royton, Oldham, England. (Source: Summary, Wikipedia, Medical News Today)

  1978-07

• Robert Edwards, a pioneer of IVF, was awarded the Nobel Prize in Physiology or Medicine for his work. (Source: Summary, Wikipedia)

  2010

• A study suggested caution regarding the use of 10 adjuncts with IVF (e.g., screening hysteroscopy, DHEA, testosterone, GH, aspirin, heparin, antioxidants, seminal plasma, PRP), recommending further evidence for their safety and effectiveness. (Source: Summary, Wikipedia)

  2019

• It was estimated that twelve million children had been born worldwide using IVF and other assisted reproduction techniques. (Source: Summary, Wikipedia)

  2023

In vitro fertilisation

In vitro fertilisation (IVF) is a process of fertilisation in which an egg is combined with sperm in vitro ("in glass"). The process involves monitoring and stimulating the ovulatory process, then removing an ovum or ova (egg or eggs) from the ovaries and enabling sperm to fertilise them in a culture medium in a laboratory. After a fertilised egg (zygote) undergoes embryo culture for 2–6 days, it is transferred by catheter into the uterus, with the intention of establishing a successful pregnancy. IVF is a type of assisted reproductive technology used to treat infertility, enable gestational surrogacy, and, in combination with pre-implantation genetic testing, avoid the transmission of abnormal genetic conditions. When a fertilised egg from egg and sperm donors implants in the uterus of a genetically unrelated surrogate, the resulting child is also genetically unrelated to the surrogate. Some countries have banned or otherwise regulated the availability of IVF treatment, giving rise to fertility tourism. Financial cost and age may also restrict the availability of IVF as a means of carrying a healthy pregnancy to term. In July 1978, Louise Brown was the first child successfully born after her mother received IVF treatment. Brown was born as a result of natural-cycle IVF, where no stimulation was made. The procedure took place at Dr Kershaw's Cottage Hospital in Royton, Oldham, England. Robert Edwards, surviving member of the development team, was awarded the Nobel Prize in Physiology or Medicine in 2010. When assisted by egg donation and IVF, many women who have reached menopause, have infertile partners, or have idiopathic female-fertility issues, can still become pregnant. After the IVF treatment, some couples get pregnant without any fertility treatments. In 2023, it was estimated that twelve million children had been born worldwide using IVF and other assisted reproduction techniques. A 2019 study that evaluated the use of 10 adjuncts with IVF (screening hysteroscopy, DHEA, testosterone, GH, aspirin, heparin, antioxidants, seminal plasma and PRP) suggested that (with the exception of hysteroscopy) these adjuncts should be avoided until there is more evidence to show that they are safe and effective.

Web Search Results

• IVF (In Vitro Fertilization): Procedure & How It Works - Cleveland Clinic

  In vitro fertilization (IVF) is a type of assisted reproductive technology (ART) where sperm and an egg are fertilized outside of the human body. IVF is a complex process that involves retrieving eggs from ovaries and manually combining them with sperm in a lab for fertilization. Several days after fertilization, the fertilized egg (now called an embryo) is placed inside a uterus. Pregnancy occurs when this embryo implants itself into the uterine wall. Advertisement [...] Gray gradient Gray gradient Search Icon Blue Cleveland Clinic logo # IVF (In Vitro Fertilization) IVF (in vitro fertilization) is a type of fertility treatment where eggs are combined with sperm outside of your body in a lab. It’s a method used by people who need help achieving pregnancy. IVF involves many complex steps and is an effective form of assisted reproductive technology (ART). Advertisement [...] The afternoon after your egg retrieval procedure, the embryologist will try to fertilize all mature eggs using intracytoplasmic sperm injection, or ICSI. This means that sperm will be injected into each mature egg. Immature eggs cannot have ICSI performed on them. The immature eggs will be placed in a dish with sperm and nutrients. Immature eggs rarely finish their maturation process in the dish. If an immature egg does mature, the sperm in the dish can then attempt to fertilize the egg.

• IVF cost: Understanding the expenses of in vitro fertilization

  In vitro fertilization (IVF) is a procedure in which a retrieved egg is fertilized with sperm in a lab and then transferred to the uterus as an embryo. An individual or couple may consider IVF if they have not been able to get pregnant through intercourse or other fertility treatments. Others pursue IVF to avoid passing on a genetic disorder or to preserve their fertility for the future. In some cases, individuals preserve their fertility because of medical treatments that may impact their [...] The fertilization process in IVF aims to mimic natural fertilization by combining eggs and sperm in a controlled laboratory environment to facilitate embryo development. A specialist will fertilize the egg by placing it in a petri dish surrounded by droplets of sperm. This method of fertilization is known as conventional insemination, which is included in the IVF base fee. However, some patients may need to use another method of fertilization called intracytoplasmic sperm injection (ICSI), in [...] Base fee (includes monitoring appointments, egg retrieval, embryo creation, and embryo transfer) $9,000–$14,000 Consultation and diagnostic testing $250–$500 Medications and injections $3,000–$7,000 Cyropreservation $1,000–$2,000 Storage fees $500–$1,000 Intracytoplasmic sperm injection $1,000–$2,000 Genetic testing $4,500–$5,500 Mock embryo transfer $240–$500 Donor sperm $1,000–$1,500 Donor eggs $20,000–$60,000 _Source:__Fertility IQ_

• In vitro fertilization (IVF) - Mayo Clinic

  In vitro fertilization, also called IVF, is a complex series of procedures that can lead to a pregnancy. It's a treatment for infertility, a condition in which you can't get pregnant after at least a year of trying for most couples. IVF also can be used to prevent passing on genetic problems to a child. [...] In vitro fertilization is the most effective type of fertility treatment that involves the handling of eggs or embryos and sperm. Together, this group of treatments is called assisted reproductive technology. IVF can be done using a couple's own eggs and sperm. Or it may involve eggs, sperm or embryos from a known or unknown donor. In some cases, a gestational carrier — someone who has an embryo implanted in the uterus — might be used. [...] During in vitro fertilization, mature eggs are collected from ovaries and fertilized by sperm in a lab. Then a procedure is done to place one or more of the fertilized eggs, called embryos, in a uterus, which is where babies develop. One full cycle of IVF takes about 2 to 3 weeks. Sometimes these steps are split into different parts and the process can take longer.

• IVF Success Rates & Statistics | PFCLA IVF Clinic Blog

  What is IVF? ------------ In Vitro Fertilization (IVF)is a medical procedure that involves fertilizing eggs with sperm outside of the body. This process is done in a laboratory setting, and the resulting embryos are then transferred to the uterus with the hope of implantation and pregnancy. IVF is often chosen by couples or individuals facing infertility challenges. Some common reasons for opting for IVF include:

• IVF: Cost, process, due date calculator, and success

  ### Health Conditions ### Health Products ### News ### Original Series ### Podcasts ### General Health ### Health Tools ### Quizzes ### About Medical News Today ### Find Community ### Follow Us # All you need to know about IVF In vitro fertilization (IVF) involves fertilizing an egg outside the body and then implanting it in a person’s uterus. IVF may help people become pregnant when other options have not worked. [...] Artificial insemination, or intrauterine insemination (IUI) is used to treat infertility. It involves direct insertion of semen into a woman's womb… An embryo transfer is part of the process of in-vitro fertilization (IVF). It may be needed if there is damage to the reproductive system due to a… Why might a doctor recommend birth control pills prior to IVF treatment? Read on to learn more about the role of oral contraceptives in IVF. [...] In 1978, Louise Brown became the first baby born via IVF conception. Robert Edwards and Patrick Steptoe, who collaborated on the procedure, are considered the pioneers of IVF. In a natural pregnancy, an egg develops and matures in the ovary. Ovulation is when the ovary releases that egg.